Happy 20th Birthday, HPV Vaccine: A Love Letter on International HPV Awareness Day 2026

By Sara Lyle-Ingersoll, Cervivor Communications Director

Happy 20th birthday, HPV vaccine!

Two decades is a big deal. Cervivor marked the same milestone last year, so we know a bit about what 20 years of impact feels like.

We still remember the excitement in 2006 when the first HPV vaccine was approved by the U.S. Food and Drug Administration (FDA). The news made the cover of Time magazine and the front page of The New York Times. But it wasn’t just another medical headline — it was a major scientific breakthrough. The idea that we could prevent cervical cancer before it ever started felt revolutionary. The hope was palpable.

Which makes today, International HPV Awareness Day — part of the International Papillomavirus Society‘s (IPVS) annual campaign to promote HPV prevention, screening, and care — a fitting moment to say happy birthday, thank you, and keep up the good work. Consider this our love letter to you, HPV vaccine. 

Why We Love You

Let’s start with the obvious: You prevent cancer.

Not symptoms. Not severity. Cancer. 

HPV is incredibly common — about 80% of people will be infected at some point in their lives. Most infections clear on their own, but some persist and can lead to cancer. Globally, HPV causes nearly all cervical cancers and contributes to cancers of the anus, oropharynx (throat), vulva, vagina, and penis. Together, HPV-related cancers account for more than 720,000 new cancer cases and roughly 350,000 deaths worldwide each year. 

When you were first approved in 2006, you protected against four HPV types, including types 16 and 18, which cause the majority of cervical cancers. Today’s version protects against nine HPV types: seven responsible for about 90% of cervical cancers, plus two that cause most genital warts. That’s pretty badass. Pardon our language.

Because prevention works best before infection occurs, vaccination is recommended between age 11 and 12, and can be given as early as 9. In this video for HPV Day 2026, IPVS envisions a world free from the cancer-causing virus — made possible in large part by you. 

Your Track Record Speaks for Itself

More than half a billion doses of the HPV vaccine have been given out worldwide, and decades of safety monitoring across multiple countries continue to confirm that you are safe. 

Any side effects are typically mild and temporary, and serious reactions are rare. The Centers for Disease Control and Prevention (CDC), the World Health Organization (WHO), and numerous independent reviews consistently affirm your safety.

And are you effective? Heck, yes! The data is just as strong. 

Countries with high vaccination coverage — think Australia, Rwanda, Sweden — have documented dramatic declines in HPV infections, genital warts, and high-grade cervical precancers among young people. 

This is no longer about projections or promises. The receipts are in. Here are just a few: 

  • A landmark 2020 study published in The New England Journal of Medicine found that Swedish girls vaccinated before age 17 had an 88% lower risk of cervical cancer compared to unvaccinated peers. 
  • In the U.K., research published in The Lancet in 2021 showed nearly a 90% reduction in cervical cancer among women vaccinated between 12 and 13.
  • In the U.S., a 2025 CDC analysis of 2008–2022 data found that cervical precancers among women 20 to 24 — the first generation routinely vaccinated — declined by roughly 80%.

That’s measurable progress and lives saved. Wow, just wow. 

U.S. rates of moderate to severe cervical precancers (CIN2+ and CIN3+) declined sharply from 2008 to 2022 among women 20 to 24 — the first generation routinely vaccinated against HPV. 

We Know It Hasn’t Always Been Easy

From the beginning, you carried more than a syringe and a schedule. You carried stigma — something anyone affected by a below-the-belt cancer understands all too well.

Because HPV is transmitted through intimate contact, conversations about the vaccine have often been wrapped up in discomfort, misinformation, and politics. Some struggle discussing a sexually transmitted virus with preteens. Others falsely claim you’re a “permission slip” for promiscuity. 

At the recent 2026 Cervical Cancer Summit — while unpacking your complicated history — Chief Medical Officer of the Association of Immunization Managers Michelle Fiscus, MD, FAAP, shared an old cartoon poking fun at the promiscuity myth. It showed a young girl receiving the HPV vaccine and saying, “I am so turned on right now.” The joke landed because the premise was so absurd.

A vaccine does not change a child’s values or lifestyle choices. It reduces their risk of cancer. Full stop.

At the 2026 Summit, Association of Immunization Managers CMO Michelle Fiscus emphasized that “misinformation remains one of our biggest barriers,” calling the promiscuity myth “farcical.”

In Case You Need to Hear This

Progress hasn’t been perfect — but that’s not on you. 

Vaccination rates vary widely by region and community. In the U.S., HPV vaccination coverage among adolescents continues to improve, but it still trails other routine adolescent vaccines like Tdap and meningococcal, according to the CDC. Research shows that a strong provider recommendation is one of the biggest factors in increasing HPV vaccination.

Globally, cervical cancer disproportionately affects women in low- and middle-income countries, where access to both vaccination and screening can be limited. The WHO’s strategy to eliminate the disease as a public health problem calls for 90% of girls to be fully vaccinated against HPV by age 15.

It’s simple math: The more people who receive you, the more lives will be saved from HPV-related cancers — which is why we’re your hype girl today and every day. 

For HPV Day, the IPVS shares a message of unity. 

Keep On Keeping On!

HPV vaccine, you have given us a tool that previous generations couldn’t even dream of. 

Twenty years ago, approving the first HPV vaccine was an act of scientific courage and public health ambition. Today, the challenge is simpler — and harder. We have to use it.

Reflecting on the momentum of the first National HPV Conference last April, Cervivor Founder and Chief Visionary Tamika Felder said, “Knowledge is power, but this is just the start. Preventable cancers like cervical cancer are on the rise because of complacency, stigma, and misinformation. The time to prevent suffering — and save lives from cervical and other HPV-related cancers — is now.”

Your moment is now. 

Happy 20th birthday to a vaccine that prevents cancer.

Here’s to a future when a cervical cancer diagnosis or, worse, a death is ancient history. 

P.S. Congratulations to the St. Jude HPV Cancer Prevention Program on five years of saving lives by increasing HPV vaccination rates! We couldn’t be prouder to call you a partner.

About the Author

SARA LYLE-INGERSOLL is a content and communications expert dedicated to transforming lived experiences into impactful stories. Her award-winning magazine feature about a close friend who passed from cervical cancer in their twenties led her to connect with Cervivor’s founder, Tamika Felder, and solidified her commitment to cervical cancer awareness and prevention. Now, as Cervivor’s Communications Director, Sara brings this mission full circle.

Marking a Milestone: Q&A on the First World Cervical Cancer Elimination Day

Is it really possible to eliminate cervical cancer—not just reduce it or manage it, but wipe it off the map for good? The World Health Organization (WHO) says yes, and has set ambitious global targets to get there by 2030.

The WHO’s 90‑70‑90 cervical cancer elimination strategy calls for:

  • 90% of girls vaccinated against HPV by age 15
  • 70% of women screened by age 35 and again at 45
  • 90% of those diagnosed receiving timely treatment

But meeting this deadline will take more than aspiration—it will take collective action. And today is a major step forward.

November 17, 2025, is the first-ever World Cervical Cancer Elimination Day, designated earlier this year by the World Health Assembly. Think of it like World AIDS Day or World Polio Day—global observances that didn’t just raise awareness, but helped spark the vaccines, screenings, and policies that pushed those diseases to the brink of eradication.

Cervivor, Inc. Founder and Chief Visionary Tamika Felder and Nigeria’s First Lady and healthcare pioneer, Dr. Zainab Shinkafi-Bagudu, were among the leaders who advocated for the day’s creation, including co-authoring a global call to action via the World Economic Forum to support it and elevate its importance on the world stage.

“I started Cervivor 20 years ago to support those affected by cervical cancer, hoping one day it wouldn’t be needed,” Tamika reflected at the time. “But too many communities are still suffering and dying from this preventable disease. A global day of recognition sends a powerful message: Awareness isn’t enough—the time for education, action, and elimination is now.”

Tamika delivers her annual “State of Cervical Cancer” address at the 2025 Cervical Cancer Summit—rallying survivors, advocates, and health leaders toward a future free from cervical cancer.

Below, we bring you an exclusive Q&A with Tamika and Dr. Bagudu, who is also Founder and CEO of the Medicaid Cancer Foundation and President-elect of the Union for International Cancer Control (UICC), answering the same questions from Maryland, USA, and Kebbi State, Nigeria, respectively. Their voices—one from the frontlines of African health equity and the other from the heart of patient advocacy—remind us: Elimination isn’t a solo act. It’s a chorus.

Q: Why does World Cervical Cancer Elimination Day matter?

Tamika: As a cervical cancer survivor, this day feels deeply personal. It represents something I once couldn’t imagine: hope for a world where no one else has to hear the words “you have cervical cancer.” When the World Health Organization declared that eliminating cervical cancer is within reach, it turned our fight from awareness into action.

For survivors, this first official World Cervical Cancer Elimination Day is a milestone that honors every story, every loss, and every victory along the way. It reminds us that our voices matter and that lived experience can guide smarter policies, stronger outreach, and more compassionate care.

Dr. Bagudu: World Cervical Cancer Elimination Day is symbolic—a rallying point for action. The WHO’s declaration that elimination is within reach shows this is an achievable reality if we commit to the right strategies.

  • Globally, it unites countries around a common goal: HPV vaccination, wider screening, and timely treatment. As President-elect of the UICC, I see this observance as a vital tool to keep cervical cancer high on the agenda, especially for low- and middle-income countries.
  • Nationally in Nigeria, it validates years of advocacy by First Ladies Against Cancer (FLAC), which I co-founded. The FLAC Screening Clinic in Kebbi is one example of how global commitments can translate into local action.
  • Personally, it is deeply meaningful. As a physician, mother, and advocate, I have seen both the devastation of late diagnosis and the hope that comes with early screening or HPV vaccination.

Ultimately, this day transforms aspiration into accountability. It tells the world: We can, and we must, eliminate this disease in our lifetime.

Dr. Bagudu, presenting a diagram of the female reproductive system to women in a rural community in Kuje, Abuja, aims to empower people in her country—and around the world—with life-saving information on cervical cancer prevention and the importance of early screening.

Q: How can a global day like this drive real change?

Tamika: We’ve seen the power of global observances before. Days like World AIDS Day and World Polio Day didn’t just raise awareness; they mobilized action, funding, and accountability. World Cervical Cancer Elimination Day can do the same.

In the United States, it can shine a light on the inequities that persist in prevention and care while inspiring innovation and collaboration. When survivors, clinicians, policymakers, and advocates unite around a shared message, we can accelerate progress toward eliminating this preventable cancer.

Dr. Bagudu: Nigeria has made important strides. The government’s rollout of the HPV vaccination program is a landmark step, protecting millions of young girls. Screening services are also expanding, with initiatives like the FLAC Screening Clinic in Kebbi showing how early detection can be brought closer to communities.

Civil society has been central. Through First Ladies Against Cancer (FLAC), we’ve sustained awareness campaigns, mobilized resources, and ensured continuity of programs. Partnerships with groups like Roche and the Clinton Health Access Initiative have strengthened diagnostics and treatment pathways. And of course, the Medicaid Cancer Foundation is at the heart of it all.

Still, challenges remain. Many rural women face barriers of distance, cost, and stigma. Shortages of trained health workers delay follow-up and treatment. And while HPV vaccines are now part of the national program, consistent supply and uptake across all states will require sustained political will and funding.

For me, this progress proves that change is possible when government, civil society, and partners work together. But it also reminds us that elimination will not happen automatically—it demands accountability, innovation, and persistence.

Q: Why is cervical cancer elimination especially urgent in low-resource regions?

Tamika: The U.S. has the knowledge and tools to prevent nearly all cervical cancers, yet persistent inequities mean prevention isn’t reaching everyone. Communities of color, people in rural areas, immigrants, people without reliable insurance, and those with language or transportation barriers face higher risks and lower access to vaccination, screening, and timely treatment. As a survivor, I know how much access, awareness, and advocacy can determine outcomes.

Elimination in the U.S. must start with equity. That means expanding vaccination access in schools and clinics, funding community-led education, and supporting policies that make screening and treatment affordable and available for everyone. Until every community is reached, we have not truly achieved elimination.

At the recent Patient Advocacy Retreat for Communities of Color in New Orleans, Tamika Felder (far right) leads survivors and advocates in grassroots outreach—bringing life-saving cervical cancer education directly into underserved communities.

Dr. Bagudu: Cervical cancer is a stark example of global health inequity. While it is increasingly rare in high-income countries, including the U.S., it remains a leading cause of cancer deaths in Africa, where women are more likely to be diagnosed late, less likely to access treatment, and more likely to die from a preventable disease.

In Nigeria, the challenges are clear:

  • Access is uneven; urban women may find screening in tertiary hospitals, but rural women face long distances, high costs, and limited awareness.
  • Stigma and cultural barriers discourage care until symptoms are advanced.
  • Health system gaps include shortages of trained personnel, diagnostic tools, and reliable vaccine supply chains.

Yet there are real opportunities. The national HPV vaccination rollout can protect millions of girls. Screening is expanding through models like the FLAC Clinic in Kebbi, which shows how state leadership can drive change. Through the Medicaid Cancer Foundation and First Ladies Against Cancer, we’ve raised awareness, supported patients, and built partnerships that strengthen care.

As President-elect of UICC, I can amplify Africa’s voice globally, while at the grassroots, we continue training health workers and engaging communities. Cervical cancer elimination is urgent because every delay costs lives—but with political will, investment, and collaboration, it is achievable, and African women must not be left behind.

Q: What progress have you seen—and what gaps remain?

Dr. Bagudu: We are at a turning point. In Nigeria and across Africa, real progress has been made against cervical cancer.

The national HPV vaccination rollout is a landmark milestone, protecting millions of girls. Screening services are expanding, with clinics like the FLAC Screening Clinic in Kebbi, and awareness campaigns are beginning to shift cultural attitudes. Treatment capacity is also improving, with more cancer centers equipped for radiotherapy and chemotherapy, while education efforts keep cancer high on the agenda.

Still, the gaps are stark. Too many women are diagnosed late, rural and low-income communities face barriers of distance, cost, and stigma, and health systems struggle with workforce shortages, supply chain issues, and limited palliative care.

This is why innovation is critical. Self-collection for HPV testing, digital health tools, mobile outreach, and task-shifting to community health workers can expand access dramatically.

The Medicaid Cancer Foundation (MCF) is helping bridge these gaps by running awareness campaigns, supporting screening in urban and rural areas, providing financial and psychosocial support through our PACE program, and advocating for sustainable funding and best practices. Beyond Nigeria, we collaborate with regional and global partners to strengthen advocacy and ensure Africa’s challenges are reflected in international strategies.

In short, progress is real, but urgency remains. With innovation, collaboration, and sustained commitment, we can close the gaps and move decisively toward eliminating cervical cancer across the continent.

Dr. Bagudu speaks at the just-concluded Medicaid Cancer Foundation disbursement of roughly $70,000 to cancer patients in Abuja, highlighting the Foundation’s commitment to patient-centered care and financial support.

Tamika: From where I stand, what’s changing most is momentum. More people are learning that HPV causes cervical cancer, vaccination rates are improving in some regions, and new technologies like HPV self-collection are showing incredible promise. Survivors are stepping into leadership roles and helping shape the national conversation about prevention and equity.

But there is still work to do. Too many people remain unaware of their risk or lack access to timely screening and treatment. Stigma and fear continue to silence conversations about cervical health. Organizations like Cervivor are helping bridge those gaps by elevating survivor voices, promoting education, and partnering with health systems to ensure innovations reach those who need them most.

Q: What message would you share on this inaugural day?

Tamika: A future without HPV-related cancers looks like prevention in every community, equity in every policy, and hope in every story. It looks like the next generation growing up protected and informed. A world without cervical cancer means no more stories like mine—and that’s the legacy I want to leave behind.

Elimination is possible, but it will take continued investment, accountability, and survivor leadership. Those of us who have lived through cervical cancer know what’s at stake, and we’re committed to making sure no one else has to.

This collage features Cervivor community members from the U.S. and around the world, showcasing powerful patient advocacy and demonstrating what survivor leadership looks like in the fight to eliminate cervical cancer.

Dr. Bagudu: On this inaugural World Cervical Cancer Elimination Day, my message is one of hope and urgency. Hope—because for the first time, we have the tools to end a cancer. Urgency—because every year of delay costs thousands of women’s lives, especially in Africa.

A future without HPV-related cancers is one where girls are routinely vaccinated, women have access to simple, affordable screening close to home, and treatment is available without stigma or financial hardship. It is a future where communities celebrate survivorship rather than mourn preventable loss.

To get there, governments must prioritize vaccination, screening, and treatment; global partners must ensure equitable access; and civil society—including the Medicaid Cancer Foundation—must continue raising awareness, supporting patients, and holding leaders accountable. Innovation, from self-collection for HPV testing to digital health tools, will also be key. 

If you found this blog post helpful, please share it with friends and family. Knowledge is power—and you may just save a life. Questions? Contact us at [email protected].