Welcome to the Clinical Trial Round Up!

It is an exciting time for science and cervical cancer! There have been limited treatments for cervical cancer for several years but now we are seeing more clinical trials opening especially for metastatic and recurrent cervical cancer patients. If you have information on a clinical trial that you would like us to include, please email us at info@cervivor.org.


innovaTV 301 – GOG 3057

The innovaTV 301 study is testing a study drug, tisotumab vedotin, for people with cervical cancer that has spread or has come back after treatment. During the study, participants will receive either the study drug or chemotherapy treatment for cervical cancer. This study drug works in a new way and is designed to target cervical cancer cells.

Visit their website here.


E7 TCR T Cells for Human Papillomavirus-Associated Cancers

Human papillomavirus (HPV) can cause cervical, throat, anal, and genital cancers. Cancers caused by HPV have a HPV protein called E7 inside of their cells. In this new therapy, researchers take a person’s blood, remove certain white blood cells, and insert genes that make them to target cancer cells that have the E7 protein. The genetically changed cells, called E7 TCR cells, are then given back to the person to fight the cancer.

Find out more here.


RTX-321

portrait of sportswoman standing in the the fields at sunrise

This Phase 1 clinical trial of RTX-321 for the treatment of HPV 16-associated cancers is an open label, multicenter, multidose, first-in-human dose escalation and expansion study designed to evaluate whether RTX-321 is tolerated, how much RTX-321 needs to be given, how often it should be given and if RTX-321 has anti-tumor activity against the cancer.

The trial is also assessing the pharmacodynamic effects of RTX-321 as measured by changes in number of CD8+ T-cells relative to baseline.

Visit their website to learn more.


Phase I & II Clinical Trial Resource

Mary Crowley Cancer Research is a specialized clinical research center that offers access to new investigational therapies through the administration of Phase I and II clinical trials. 

  • Personalized approach to cancer research
  • Clinical trials are matched to molecular information found within each cancer patient
  • Qualified Physician Investigators add to the understanding of what drives cancer and create innovative research applications that attack these drivers
  • Patient-centric focus brings the newest clinical trial options to patients at a rapid pace

Visit their website to view current Phase I and II clinical trial opportunities.


Join us for an upcoming event over clinical trials!

Don’t miss out on learning more about clinical trials and the patient experience! Join us for a collaborative event with SQZ Biotechnologies! You’ll hear the latest on cervical cancer and clinical trials from the first-hand experiences of an SQZ researcher as well as a patient focused panel. 

Register today!

Reaching That First Big Milestone

Five years? How is it possible?

Five years. It seems like much longer yet it’s still so fresh in my mind. I have spent so much time processing through what happened to me – the good and the bad. Where there was darkness, there was so much beauty to equal it out. Cue the universe’s synchronicities and all the cardinal sightings.

Six years ago, I was diagnosed with cervical cancer for the first time at age 24. They found spots in my lungs after only being six months into remission. It was truly devastating! I was back in school full-time, working full-time, and trying to regain some normalcy.

But life had other plans for me.

I went through diagnostic test after diagnostic test to confirm it was cancer. Indeed, I would be facing my mortality once again. I will never forget the words my oncologist spoke to me after I received my first three treatments, “There are 7-9% of women who experience a complete interval response to treatment. You are one of those 7-9%. You don’t have any evidence of disease.”

I knew I had been given such an incredible gift and that I must not waste this second chance at life. What I didn’t expect was to find my voice as loud as I’ve made it. I stumbled across Cervivor through a hashtag on Instagram – I didn’t see this as a coincidence. I fundraised my way to Cervivor School in 2017 where I flew out to Delray Beach, Florida and learned how to use my voice in advocacy. The rest is history.

I’m still processing through many of accomplishments that I’ve experienced over the last five years including the idea that I’ve graduated three times despite my diagnosis and treatments, and that I’ve reached my first big cancerversary milestone. I’ve jumped at every Cervivor opportunity to be a part of change from cancer panel speaking opportunities to proclamation signings with Iowa’s governor for Cervical Cancer Awareness Month (January) to volunteering with the American Cancer Society Cancer Action Network (ACSCAN) to protect or improve policies related to cancer care. I also serve as a leader with Above and Beyond Cancer to make the Adolescent and Young Adult (AYA) community visible locally. Because of this work, I’ve been given three awards from Cervivor, ACSCAN, and Above and Beyond Cancer.

I know I wouldn’t be able to do this work alone, it takes a village to make a difference – to make change happen. It is exhausting and it can take a toll but it is also truly rewarding to see our impact taking place across the globe. I’ve met so many resilient and passionate advocates (along with their family members) – some are still with us while others have succumbed to their diagnoses. As a survivor and patient advocate, I had to accept and understand that this was going to be a common occurrence in our community but it didn’t make it suck any less.

However challenging this work may be, I wouldn’t trade this personal and professional growth for anything. Here’s to 5 years cancer free!

Morgan is a metastatic recurrent cervical cancer survivor, a 3x award winning patient advocate, and our Community Manager for Cervivor. She resides in Iowa with her boyfriend, Tony, their cat, Jeezy, and dachshund, Sassy. Morgan continues to advocate tirelessly in hopes her story can help others.